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|Research Applications For Antibody Labeling February 2 http://www.cheapmexicosoccerjersey.com/alfredo-talavera-jersey/ , 2014 | Author: Marissa Velazquez | Posted in Education
Introduction: Antibody labeling is a valuable and versatile technique used in medicine and research. To put it simply, an antibody is a type of protein that an animal makes in response to a foreign antigen. This may be a bacterium, a virus or other substance present in the blood that is recognized as non-self.
There is not a single process in the mammalian body that can occur without the cooperation of one or more proteins. These are huge molecules, also known as macromolecules, that are made from smaller chemical units known as amino acids. The order in which the individual amino acids are strung together dictates the 3D shape of the finished protein. It is the specific shape of a protein that determines its function in the organism.
Enzymes are necessary to catalyze, or speed up, the millions of reactions that take place in our cells every second of every minute of every hour of every day of our lives. In fact http://www.cheapmexicosoccerjersey.com/alejandro-palacios-jersey/ , when we eat protein, there are enzymes that help to break down each molecule of protein into its own amino acids. These amino acids are then used to make new proteins. Immunoglobulins are a different type of protein.
Manufacture of antibodies: In the mammalian body, antibodies, also known as immunoglobulins (Igs) are synthesized by a particular type of cell in the immune system, the “B” cell. B cells are able to detect foreign molecules and produce Igs to neutralize threats. This is the basis of immunization.
There is just enough antigen present to stimulate Ig production but not enough to induce illness. If the same antigen is encountered subsequently, in other words, if the person becomes infected with virus http://www.cheapmexicosoccerjersey.com/adrian-aldrete-jersey/ , the B cells will be stimulated to produce loads of antibodies to quell the infection.
In the research lab, Ig synthesis begins with the injection of antigen into an animal. Rabbits are often the animal used, although other mamalian species like mice or donkeys are also used. The animal’s B cells produce antibodies to the antigen and are then harvested from their blood. Sometimes the primary antibody is conjugated to a second antibody to amplify the visual signal and then attached to a molecular probe.
More often, the primary Ig is attached to a second antibody that has been raised in a different animal, and then attached to the molecular probe, for example a fluorescent marker. When the whole three-piece molecular system is exposed to ultraviolet light, it emits fluorescence that is detected as a brilliant flash of color. Antibodies may be raised to different antigens and different colored fluorescent markers to confirm the identity of the cells to which it is later applied.
Antibody labeling is a frequently used tool in the research of neuro-oncology http://www.cheapmexicosoccerjersey.com/ , or brain tumors. Cells are grown on microscope slides in a special culture medium, to which different substances, such as growth factors, may be added. The cells are then labeled with the fluorescent preparations and a snapshot is viewed of specific proteins present in the cell.
You can visit the website www.columbiabiosciences for more helpful information about Research Applications For Antibody Labeling
Hyde Park is one of London's most famous parks. It is situated north of the River Thames and shares a border with Kensington Gardens to the west. Many people who visit London decide to pay a visit to Hyde Park, and there are certainly plenty of reasons to do so.
Firstly you may be aware that the park contains a large lake called the Serpentine. This lake is famous for many different reasons. It will be involved in the Olympics when they take place later in 2012. It is fed by a spring that is naturally occurring underground. It is also the place where members of the local swimming club meet on Christmas morning, to take a dip in the waters and race to see who can swim 100 yards in the fastest time.
A road called West Carriage Drive cuts through the park and it also cuts across the lake. The western portion of the water is called the Long Water, as it is a long and much thinner body of water than the Serpentine. You can hire a boat on the lake if you wish http://www.cheapmexicosoccerjersey.com/yasser-corona-jersey/ , and if you have the energy to row around the area provided! It does give you an excellent opportunity to enjoy a different view of Hyde Park other than the one you will get on land.
If you want to spend some time exploring the park you should look for accommodation Hyde Park. This is available close by and you can opt to stay in a 4 star hotel near Hyde Park if you wish. There is plenty more to do locally too, so accommodation Hyde Park might actually be a smart choice in more ways than one.
If the weather is good you can look forward to exploring everything that the park has to offer. You might want to take a walk around its perimeter for example. If you take in Kensington Gardens as well you can walk around in a circular fashion for several miles before returning to the point where you started. This is a nice challenge, especially as you could opt to stop in Hyde Park for a picnic when you are perhaps halfway round. This will give you more time to burn off your lunch afterwards!
As you can see Hyde Park is a delightful place to enjoy and you will see many other people making the most of this green space in London as well. Joggers and cyclists also make use of the park, so be sure you don't get in their way. There are plenty of places to have picnics and once you are done you can return to your 4 star hotel near Hyde Park to enjoy a nice relaxing evening in.
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